基本信息
林富春  男  博导  中国科学院精密测量科学与技术创新研究院
电子邮件: fclin@wipm.ac.cn
通信地址: 湖北省武汉市武昌区小洪山西30号
邮政编码: 430071

研究领域

神经影像、机器学习

招生信息

招收博士研究生,硕士研究生


招生专业
070302-分析化学
086000-生物与医药
招生方向
磁共振神经影像
脑科学,生物医学工程
机器学习

教育背景

2003-09--2006-07   中国科学院自动化研究所   博士
2000-09--2003-07   华中科技大学   硕士
1996-09--2000-07   中国地质大学(武汉)   本科
学历
博士研究生
学位
博士

工作经历

2006.7-至今: 中国科学院武汉物理与数学研究所 助理研究员/副研究员/研究员

2015-08~2016-09,纽约州立大学布法罗分校, 合作研究

专利与奖励

  1. 湖北省科技进步二等奖 2018
  2. 中国科学院卢嘉锡青年人才奖 2011
  3. 湖北省科技进步奖二等奖 2010
  4. 武汉市科技进步奖二等奖2010
  5. 全国优秀博士学位论文提名奖 2009
  6. 中国科学院优秀博士学位论文 2008
  7. 教育部科技进步奖二等奖 2008
  8. 湖北省科技进步奖二等奖 2008
  9. 中华医学科技奖二等奖 2007
  10. 中国科学院院长优秀奖 2006

出版信息

  1. Xianxin Qiu, Xu Han, Yao Wang, Weina Ding, Yawen Sun, Hao Lei, Yan Zhou*, and Fuchun Lin*. Sex differences in alterations of brain functional network in tobacco use disorder. Nicotine Tob Res, 2024; accepted. doi: 10.1093/ntr/ntae002.
  2. Yiwen Wang, Guangyao Wu, Zhi Wen, Hao Lei, and Fuchun Lin*. Highly active antiretroviral therapy-related effects on morphological connectivity in HIV. AIDS, 2024; 38(1): 207-215.
  3. Xianxin Qiu, Xu Han, Yao Wang, Weina Ding, Yawen Sun, Hao Lei, Yan Zhou*, and Fuchun Lin*. Interaction effects between smoking and internet gaming disorder on resting-state functional connectivity of the ventral tegmental area and hippocampus. Front Neurosci, 2023; 17: 1270014.
  4. Shengjuan Wu, Zhi Wen, Wenzhong Yang, Chengcheng Jiang, Yurong Zhou, Zhiwei Zhao, Aiqin Zhou, Xinglian Liu, Xiaoyan Wang, Yue Wang, Hong Wang*, and Fuchun Lin*. Potential dynamic regional brain biomarkers for early discrimination of autism and languge development delay in  toddlers. Front Neurosci, 2023; 16: 1097244.
  5. Xianxin Qiu, Xu Han, Yao Wang, Weina Ding, Yawen Sun, Hao LeiYan Zhou* and Fuchun Lin*.  Reciprocal modulation between cigarette smoking and internet gaming disorder on participation coefficient within functional brain networks. Brain Imaging Behav, 2022; 16(5):2011-2020.
  6. Yajuan Wang, Yingshuang Wang, Lihong Bu, Shaoyang Wang, Xinhui Xie, Fuchun Lin*, and Zheman Xiao*. Functional connectivity features of resting-state fMRI may distinguish migraine from tension-type headache. Front Neurosci, 2022; 16: 851111.
  7. Zhi Wen, Xu Han, Yao Wang, Weina Ding, Yawen Sun, Yan Kang, Yan Zhou, Hao Lei, and Fuchun Lin*. Sex-dependent alterations of regional homogeneity in cigarette smokers. Front Psychiarty, 2022; 13: 874893.
  8. Fuchun Lin*, Xu Han, Yao Wang, Weina Ding, Yawen Sun, Yan Zhou* and Hao Lei. Sex-specific effects of cigarette smoking on caudate and amygdala volume and resting-state functional connectivity. Brain Imaging Behav, 2021; 15(1): 1-13.
  9. Tao Song, Wei Chen, Xi Chen, Hui Zhang, Yijuan Zou, Hao Wu, Fuchun Lin, Liyi Ren, Yan Kang, and Hao Lei.  Repeated fluoxetine treatment induces transient and long-term astrocytic plasticity in the medial prefrontal cortex of normal adult rats. Prog Neuropsychopharmacol Bio Psychiatry. 2021; 107: 110252.
  10. Ronghui Li, Xuxia Wang, Fuchun Lin, Tao Song, Xutao Zhu, and Hao Lei. Mapping Accumulative Whole-Brain Activities During Environmental Enrichment With Manganese-Enhanced Magnetic Resonance Imaging. Neuroimage, 2020; 210: 116588.
  11. Xianxin Qiu, Xu Han, Yao Wang, Weina Ding, Yawen Sun, Yan Zhou, Hao Lei, and Fuchun Lin*. Interaction between smoking and internet gaming disorder on spontaneous brain activity. Front Psychiatry, 2020; 11:586114.
  12. Fuchun Lin*, Guangyao Wu, Ling Zhu, and Hao Lei. Region-specific changes of insular cortical thickness in heavy smokers. Front Hum Neurosci, 2019, 13: 265.
  13. Yawen Sun, Yao Wang, Xu Han, Wenqing Jiang, Weina Ding, Mengqiu Cao, Yasong Du, Fuchun Lin, Jianrong Xu, and Yan Zhou. Sex differences in resting-state cerebral activity alterations in internet gaming disorder. Brain Imaging Behav, 2019; 13(5): 1406-1417.
  14. Fuchun Lin, Robert Zivadinov, Jesper Hagemeier, Bianca Weinstock-Guttman, Caila Vaughn, Sirin Gandhi, Dejan Jakimovski, Hanneke E. Hulst, Ralph H.B. Benedict, Niels Bergsland, Tom Fuchs, and Michael G. Dwyer. Altered nuclei-specific thalamic functional connectivity patterns in multiple sclerosis, and their associations with fatigue and cognition. Mult Scler, 2019; 25(9): 1243-1254.
  15. Robert Zivadinov, Eleonora Tavazzi, Niels Bergsland, Jesper Hagemeier, Fuchun Lin, Michael G. Dwyer, Ellen Carl, Channa Kolb, David Hojnacki, Deepa Ramasamy, Jacqueline Durfee, Bianca Weinstock-Guttman, and Ferdinand Schweser. Brain Iron by Quantitative MRI is associated with Disability in Multiple Sclerosis. Radiology, 2018; 289(2): 487-496.
  16. Xu Han, Xiaowei Wu, Yao Wang, Yawen Sun, Weina Ding, Mengqiu Cao, Yasong Du, Fuchun Lin*, Yan Zhou*. Alterations of resting-state static and dynamic functional connectivity of the dorsolateral prefrontal cortex in subjects with internet gaming disorder. Front Hum Neurosci, 2018: 41.
  17. Jielan Li, Lei Gao, Zhi Wen, Jing Zhang, Pangying Wang, Ning Tu, Hao Lei, Fuchun Lin, Xi'en Gui and Guangyao Wu. Structural Covariance of Gray Matter Volume in HIV Vertically Infected Adolescents. Sci Rep, 2018; 8(1):1182.
  18. Jesper Hagemeier, Murali Ramanathan, Ferdinand Schweser, Michael G. Dwyer, Fuchun Lin, Niels Bergsland, Bianca Weinstock-Guttman, and Robert Zivadinov. Iron-related gene variants and brain iron in multiple sclerosis and healthy individuals. NeuroImage Clin, 2018, 17:530-540.
  19. Ferdinand Schweser, Ana Luiza Raffaini Duarte Martins, Jesper Hagemeier, Fuchun Lin, Jannis Hanspach, Bianca Weinstock-Guttman, Simon Hametner, Niels Bergsland,  Michael G. Dwyer, and Robert Zivadinov. Mapping of thalamic magnetic susceptibility in multiple sclerosis indicates decreasing iron with disease duration: A proposed mechanistic relationship between inflammation and oligodendrocyte vitality. Neuroimage, 2018, 167: 438-452.
  20. Zhi Wen, Jie Zhang, Jielan Li, Jiankun Dai, Fuchun Lin, Guangyao Wu. Altered Activation in Cerebellum Contralateral to Unilateral Thalamotomy May Mediate Tremor Suppression in Parkinson's Disease: A Short-Term Regional Homogeneity fMRI Study. PLoS One, 2016, 11(6): e0157562.
  21. Wu H, Wang X, Gao Y, Lin F, Song T, Zou Y, Xu L, and Lei H. NMDA receptor antagonism by repetitive MK801 administration induces schizophrenia-like structural changes in the rat brain as revealed by voxel-based morphometry and diffusion tensor imaging. Neuroscience,  2016, 322: 221-233.
  22. Jielan Li, Guangyao Wu*, Zhi Wen, Jing Zhang, Hao Lei, Xi’en Gui, and Fuchun Lin*. WM development is potentoially influenced in adolescents with vertically-transmitted HIV infections: A tract-based spatial statistics study. AJNR Am J Neuroradiol, 2015, 36(11): 2163-2169.
  23. Fuchun Lin, Yan Zhou, Yasong Du, Lindi Qin, Zhimin Zhao, Jianrong Xu, and Hao Lei.  Aberrant corticostriatal functional circuits in adolescents with Internet addiction disorder. Front Hum Neurosci, 2015, 9: 356.
  24. Guangyao Wu*, Shiqi Yang, Ling Zhu, and Fuchun Lin*. Altered spontaneous brain activity in heavy smokers revealed by regional homogeneity. Psychopharmacology, 2015, 232(14): 2481-2489.
  25. Xuxia Wang, Fuchun Lin, Yunling Gao, and Hao Lei. Bilateral common carotid artery occlusion induced brain lesions in rats: A longitudinal diffusion tensor imaging study. Magn Reson Imaging 2015, 33(5):551-558.
  26. Fuchun Lin, and Hao Lei. Structural Brain Imaging and Internet Addiction. Internet Addiction, Neuroscientific Approaches and Therapeutical Interventions, Christian Montag and Martin Reuter (Editors), Springer, Switzerland 2015, 21-42.
  27. Ling Zhu, Guangyao Wu*, Xin Zhou, Jielan Li, Zhi Wen, and Fuchun Lin*. Altered spontaneous brain activity in patients with acute spinal cord injury revealed by resting-state functional MRI. PLoS ONE, 2015, 10(3): e0118816.
  28. Fuchun Lin, Guangyao Wu, Ling Zhu, and Hao Lei. Altered brain functional networks in heavy smokers. Addict Biol, 2015, 20(4): 809-819.
  29. Yinwei Song, Ketao Mu, Junming Wang, Fuchun Lin*, Zhiqi Chen, Xiaoqin Yan, Yonghong Hao, Wenzhen Zhu*, and Hong Zhang*. Altered spontaneous brain activity in primary open angle glaucoma: A resting-state functional magnetic resonance imaging study. PLoS ONE, 2014, 9(2): e89493.
  30. Zhiqi Chen, Junming Wang, Fuchun Lin, Hui Dai, Ketao Mu, and Hong Zhang. Correlation between lateral geniculate nucleus atrophy and damage to the optic disc in glaucoma J Neuroradiol, 2013, 40(4):281-287.
  31. Shuxia Wang, Dai Shan, Jiankun Dai, Haichen Niu, Yuanye Ma, Fuchun Lin, and Hao Lei. Anatomical MRI templates of tree shrew brain for volumetric analysis and voxel-based morphometry. J Neurosci Methods, 2013, 220(1): 9-17.
  32. Liqin Yang#, Fuchun Lin#, Yan Zhou, Jianrong Xu, Chunshui Yu, Wen-Ju Pan, and Hao Lei. Iterative Cross-correlation Analysis of Resting State Functional Magnetic Resonance Imaging Data. PLoS ONE, 2013, 8(3): e58653.
  33. Fuchun Lin, Guangyao Wu, Ling Zhu, and Hao Lei. Heavy smokers show abnormal microstructural integrity in the anterior corpus callosum: A diffusion tensor imaging study with tract-based spatial statistics. Drug Alcohol Depend, 2013, 129(1-2): 82-87.
  34. Zhiqi Chen#, Fuchun Lin#, Junming Wang, Zheng Li, Hui Dai, Ketao Mu, Jian Ge, and Hong Zhang. Diffusion tensor magnetic resonance imaging reveals visual pathway damage that correlates with clinical severity in glaucoma. Clin Experiment Ophthalmol, 2013, 41(1): 43-49.
  35. Mingming Huang, Lifeng Gao, Liqin Yang, Fuchun Lin, and Hao Lei. Abnormalities in brains of streptozotocin-induced type 1 diabetic rats revealed by diffusion tensor imaging. Neuroimag Clin, 2012, 1(1): 57-65.
  36. Fuchun Lin, Yan Zhou, Yasong Du, Lindi Qin, Zhimin Zhao, Jianrong Xu, and Hao Lei. Abnormal white matter integrity in adolescents with Internet addiction disorder: A tract-based spatial statistics study. PLoS ONE, 2012, 7(1): e30253.
  37. Fuchun Lin, Shenhong Weng, Baojun Xie, Guangyao Wu, and Hao Lei. Abnormal frontal cortex white matter connections in bipolar disorder: A DTI tractography study. J Affect Disord, 2011, 131(1-3): 299-306.
  38. Fuchun Lin, Chunshui Yu, Yaou Liu, Kuncheng Li, and Hao Lei. Diffusion tensor group tractography of the corpus callosum in clinically isolated syndrome. AJNR Am J Neuroradiol, 2011, 32(1): 92-98.
  39. Yan Zhou#, Fuchun Lin#, Yasong Du, Lingdi Qin, Zhimin Zhao, Jianrong Xu, and Hao Lei. Gray matter abnormalities in Internet addiction: A voxel-based morphometry study. Eur J Radiol, 2011, 79(1): 92-95.
  40. Chunshui Yu, Fuchun Lin, Li Zhao, Jing Ye, and Wen Qin. Occult white matter damage contributes to intellectual disability in tuberous sclerosis complex. Intelligence, 2009, 37(2): 174-180.
  41. Chunshui Yu, Fuchun Lin, Yaou Liu, Yunyun Duan, Hao Lei, and Kuncheng Li. Histogram analysis of diffusion indices in clinically isolated syndromes and relapsing-remitting multiple sclerosis. Eur J Radiol, 2008, 68(2):328-334.
  42. Yan Zhou#, Fuchun Lin#, Jiong Zhu, Zhiguo Zhuang, Yansheng Li, Jing Tao, Lijun Qian,  Jianrong Xu, and Hao Lei. Whole brain diffusion tensor imaging histogram analysis in vascular cognitive impairment. J Neurol Sci, 2008, 268(1-2): 60-64.
  43. Chunshui Yu, Fuchun Lin, Kuncheng Li, Tianzi Jiang, Wen Qin, Hong Sun, and Piu Chan. Pathogenesis of normal-appearing white matter damage in neuromyelities optica: diffusion-tensor MR imaging. Radiology, 2008, 246(1):222-228.
  44. Wenju Pan, Guangyao Wu, Chunxia Li, Fuchun Lin, Junmo Sun, and Hao Lei. Progressive atrophy in the optic pathway and visual cortex of early blind chinese adults: a voxel-based morphometry magnetic resonance imaging study. NeuroImage, 2007, 37(1): 212-220.
  45. Fuchun Lin, Chunshui Yu, Tianzi Jiang, Kuncheng Li, and Piu Chan. Diffusion tensor tractography based group mapping of the pyramidal tract in relapsing-remitting multiple sclerosis patients. AJNR Am J Neuroradiol, 2007, 28(2): 278-282.
  46. Fuchun Lin, Chunshui Yu, Tianzi Jiang, Kuncheng Li, Xiaobo Li, Wen Qin, Hong Sun, and Piu Chan. Quantitative analysis along the pyramidal tract by length-normalized parameterization based on diffusion tensor tractography: application to patients with relapsing neuromyelitis optica. NeuroImage, 2006, 33(1): 154-160.
  47. Fuchun Lin, Chunshui Yu, Tianzi Jiang, Kuncheng Li, Chaozhe Zhu, Wanlin Zhu, Wen Qin, Yunyun Duan, Yun Xuan, Hong Sun, and Piu Chan. Discriminative analysis of relapsing neuromyelitis optica and relapsing-remitting multiple sclerosis based on two-dimensional histogram from diffusion tensor imaging. NeuroImage, 2006, 31(2): 543-549.
  48. Chunshui Yu, Fuchun Lin, Kuncheng Li, Tianzi Jiang, Chaozhe Zhu, Wen Qin, Hong Sun, and Piu Chan. Diffusion tensor imaging in the assessment of normal-appearing brain tissue damage in relapsing neuromyelitis optica. AJNR Am J Neuroradiol, 2006, 27(5): 1009-1015.

科研活动


科研项目
( 1 ) 基于扩散张量成像对视神经脊髓炎与多发性硬化的鉴别新方法研究, 负责人, 国家任务, 2009-01--2011-12
( 2 ) 额叶-纹状体神经回路与吸烟成瘾戒断、复吸关系的磁共振影像研究, 负责人, 国家任务, 2016-01--2019-12
( 3 ) 尼古丁依赖戒断与复吸的神经机制的磁共振影像学研究, 负责人, 中国科学院计划, 2017-05--2022-12

指导学生

已指导学生

辛红涛  硕士研究生  085238-生物工程  

胡赢丹  硕士研究生  070302-分析化学  

邱先鑫  博士研究生  070302-分析化学  

现指导学生

蔡悦  博士研究生  070300-化学  

王奕雯  博士研究生  070300-化学  

李修贤  硕士研究生  070300-化学  

江蕾  博士研究生  070300-化学  

郭浩东  硕士研究生  086000-生物与医药