Chen, Yan 
Shenzhen Institutes of Advanced Technology
Telephone: 0755-86392254
Address: 1068 Xueyuan Ave. SZ University Town, Shenzhen, China
Postcode: 518055

Research Areas

Microfluidic applications in biochemical analysis
Optofluidic devices for biosensing
Point-of-care diagnostic devices
Advanced nanofabrication technologies


1998-2002 Tsinghua University, Biomedical Engineering, B.S.
2002-2008 California Institute of Technology, Bioengineering, Ph.D.


Work Experience
2008-2009 California Institute of Technology, Postdoctoral Researcher
2009-2010 Princeton University, Postdoctoral Researcher
Teaching Experience

Introduction to Biomedical Microdevices, 2016



1.       B. Zhang, H. Xu, Y. Huang, W. Shu, H. Feng, J. Cai, J. F. Zhong, and Y. Chen, "Improving single-cell transcriptome sequencing efficiency with a microfluidic phase-switch device," Analyst 144, 7185-7191 (2019). (IF=4.019)

2.       J. Wang, K. Deng, C. Zhou, Z. Fang, C. Meyer, K. U.-A. Deshpande, Z. Li, X. Mi, Q. Luo, B. D. Hammock, C. Tan, Y. Chen, and T. Pan, "Microfluidic cap-to-dispense (μCD): a universal microfluidic–robotic interface for automated pipette-free high-precision liquid handling," Lab on a Chip 19, 3405-3415 (2019). (IF=6.914)

3.       Y. Chen, J. Millstein, Y. Liu, G. Y. Chen, X. Chen, A. Stucky, C. Qu, J. Fan, X. Chang, A. Soleimany, K. Wang, J. Zhong, J. Liu, F. D. Gilliland, Z. Li, X. Zhang, and J. F. Zhong, "Single-Cell Digital Lysates Generated by Phase-Switch Microfluidic Device Reveal Transcriptome Perturbation of Cell Cycle," ACS Nano, 12(5), 4687-4694 (2018). (IF=13.942)

4.       Y. Zeng, L. Gao, X. Luo, Y. Chen, M. H. Kabeer, X. Chen, A. Stucky, W. G. Loudon, S. C. Li, X. Zhang, J. F. Zhong,, "Single Microfluidic enrichment of plasma cells improves treatment of multiple myeloma," Molecular Oncology, 12, 1004-1011 (2018). (IF=5.264)

5.       J. Li, R. P. Carney, R. Liu, J. Fan, S. Zhao, Y. Chen, K. S. Lam, and T. Pan, "Microfluidic Print-to-Synthesis Platform for Efficient Preparation and Screening of Combinatorial Peptide Microarrays," Analytical Chemistry, 90, 5833-5840 (2018). (IF=6.32)

6.       Q. Luo, L. Liu, C. Yang, J. Yuan, H. Feng, Y. Chen, P. Zhao, Z. Yu, and Z. Jin, "A rapid, ratiometric, enzyme-free, and sensitive single-step miRNA detection using three-way junction based FRET probes," Nanotechnology 29, 114001 (2018).  (IF=3.44)

7.       H. Feng, W. Shu, H. Xu, B. Zhang, B. Huang, J. Wang, W. Jin and Y. Chen*, "Two-Directional Tuning of Distributed Feedback Film Dye Laser Devices," Micromachines 8(12), 362, (2017). (IF=1.833)

8.       C. Yu, F. Tang, X. Qian, Y. Chen, Q. Yu, K. Ni and X. Wang, "Multi-channel microfluidic chip coupling with mass spectrometry for simultaneous electro-sprays and extraction," Scientific Reports, 7, 17389, (2017). (IF=4.259)     

9.       W. Zhou, J. Wang, K. Wang, B. Huang, L. Niu, F. Li, F. Cai, Y. Chen, X. Liu, X. Zhang, H. Cheng, L. Kang, L. Meng and H. Zheng, "Ultrasound neuro-modulation chip: activation of sensory neurons in Caenorhabditis elegans by surface acoustic waves," Lab on a Chip 17, 1725-1731 (2017). (IF=6.045)

10.   H. Liu, W. Shu, Z. Liu, B. Zhang, H. Feng, Y. Chen*, "A simple method of constructing microfluidic solid-state quantum dot molecular beacon array for label-free DNA detection," Microfluidics and Nanofluidics, 21 (67), (2017). (IF=2.344)

11.   J. Jiang, H. Zhao, W. Shu, J. Tian, Y. Huang, Y. Song, R. Wang, E. Li, D. Slamon, D. Hou, X. Du, L. Zhang*, Y. Chen*, Q. Wang*, "An integrated microfluidic device for rapid and high-sensitivity analysis of circulating tumor cells," Scientific Reports, 7, 42612 (2017). (IF=4.259)

12.   C. Yu, X. Qian, Y. Chen, Q. Yu, K. Ni, X. Wang, "Microfluidic self-aspiration sonic-spray ionization chip with single and dual ionization channels for mass spectrometry," RSC Advances 6, 50180-50189, (2016). (IF=3.289)

13.   C. Yu, X. Qian, Y. Chen, Q. Yu, K. Ni, X. Wang, "Three-dimensional electro-sonic flow focusing ionization microfluidic chip for mass spectrometry," Micromachines 6 (12), 1890-1902 (2015). (IF=1.269).

14.   H. Feng, W. Shu, X. Chen Y. Zhang, Y. Lu, L. Wang and Y. Chen*, "Development of a microfluidic platform with integrated power splitting waveguides for optogenetic neural cell stimulation," Biomedical Microdevices 17 (101), (2015). (IF=2.877)

15.   X. Qian*, J. Xu, C. Yu, Y. Chen*, Q. Yu, K. Ni, and X. Wang, "A Reliable and Simple Method for Fabricating a Poly(Dimethylsiloxane) Electrospray Ionization Chip with a Corner-Integrated Emitter," Sensors 15, 8931-8944 (2015). (IF=2.245)

16.   J. Gao, J. Du, W. Zhang, B. Zhang, Z. Liu, Y. Chen*, and X. Xu*, "A Simple Fabricated Microfluidic Chip for Rapid Capture of Circulating Tumor Cells," Acta Chimica Sinica 72, 69-74 (2014). (IF=0.874)

17.   L. Meng, F. Cai, P. Jiang, Z. Deng, F. Li, L. Niu, Y. Chen, J. Wu, and H. Zheng, "On-chip targeted single cell sonoporation with microbubble destruction excited by surface acoustic waves," Applied Physics Letters 104, 073701 (2014). (IF=3.38)

18.   Z. Liu, W. Zhang, F. Huang, H. Feng, W. Shu, X. Xu, and Y. Chen*, "High throughput capture of circulating tumor cells using an integrated microfluidic system," Biosensors & bioelectronics 47, 113-119 (2013). (IF=5.437)

19.   Z. Liu, F. Huang, J. Du, W. Shu, H. Feng, X. Xu, and Y. Chen*, "Rapid isolation of cancer cells using microfluidic deterministic lateral displacement structure," Biomicrofluidics 7, 011801 (2013). (IF=3.385)

20.   Y. Chen*, B. Zhang, H. Feng, W.Shu, G. Y. Chen, and J. F. Zhong, "An automated microfluidic device for assessment of mammalian cell genetic stability," Lab on a Chip 12, 3930-3935 (2012). (IF=5.67)



张诗昀  硕士研究生  085600-材料与化工