基本信息

张鹏飞 男 硕导 中国科学院深圳先进技术研究院
电子邮件: pf.zhang@siat.ac.cn
通信地址: 深圳市南山区学苑大道1068号
邮政编码:
电子邮件: pf.zhang@siat.ac.cn
通信地址: 深圳市南山区学苑大道1068号
邮政编码:
研究领域
1) 聚集诱导发光
2) 纳米生物分析
3) 纳米医学
4) 生物材料
招生信息
1) 分析化学
2) 功能材料
3) 化学生物学/纳米生物学
招生专业
0703Z1-化学生物学070305-高分子化学与物理083100-生物医学工程
招生方向
聚集发光材料核酸纳米技术微纳机器人
教育背景
2015-08--2018-11 香港科技大学 博士研究生2002-09--2009-07 湖南大学 硕士研究生
学历
博士
工作经历
工作简历
2018-12~现在, 中国科学院深圳先进技术研究院, 副研究员2011-07~2015-08,中国科学院深圳先进技术研究院, 助理研究员2009-07~2011-07,中国科学院深圳先进技术研究院, 研究助理
教授课程
化学生物学
专利与奖励
奖励信息
(1) 纳米智能材料的化学标记与生物示踪研究, 二等奖, 省级, 2016(2) 纳米生物智能材料的肿瘤诊疗一体化研究, 二等奖, 市地级, 2015
专利成果
( 1 ) LUMINOGENS FOR BIOLOGICAL APPLICATIONS, 发明, 2017, 第 5 作者, 专利号: WO2018108070( 2 ) NIR-II Emissive Luminogens, 发明, 2019, 第 2 作者, 专利号: WO2019238121A1( 3 ) AIEGENS FOR CANCER CELL IMAGING, 发明, 2017, 第 5 作者, 专利号: WO2018014865.
出版信息
长期从事多功能发光纳米材料合成、修饰及其生物分析及医学相关应用研究,已在J.Am.Chem.Soc.(化学顶级期刊), Angewandte Chemie International Edition, (化学顶级期刊), Analytical Chemistry (分析化学顶级期刊), Advanced Materials(材料科学顶级期刊), Advanced Functional Materials, ACS NANO, Biomaterials等国际期刊发表发表论文50 余篇(第一作者/通讯作者文章15篇,其中影响因子大于10的论文4篇)
发表论文
(1) Fluorescence Self‐Reporting Precipitation Polymerization Based on Aggregation‐Induced Emission for Constructing Optical Nanoagents, Angewandte Chemie International Edition, 2020, 第 1 作者(2) Ratiometric Photoacoustic Chemical Sensor for Pd2+ Ion, Analytical Chemistry, 2020, 通讯作者(3) Highly Stable and Bright NIR-II AIE Dots for Intraoperative Identification of Ureter, ACS Appl. Mater. Interfaces, 2020, 第 1 作者(4) Development of AIEgen–montmorillonite nanocomposite powders for computer-assisted visualization of latent fingermarks, Materials Chemistry Frontiers, 2020, 通讯作者(5) On-site visual discrimination of transgenic food by water-soluble DNA-binding AIEgens, Materials Chemistry Frontiers, 2019, 通讯作者(6) Mitochondria-Localized Self-Reporting Small-Molecule-Decorated Theranostic Agents for Cancer-Organelle Transporting and Imaging, ACS Applied Bio Materials, 2019, 通讯作者(7) Lysosome-Targeting Red-Emitting Aggregation-Induced Emission Probe with Large Stokes Shift for Light-Up in Situ Visualization of β-N-Acetylhexosaminidase, Analytical Chemistry, 2019, 第 4 作者(8) An Easily Available Ratiometric Reaction-Based AIE Probe for Carbon Monoxide Light-up Imaging, Analytical Chemistry, 2019, 通讯作者(9) Monitorable Mitochondria-Targeting DNAtrain for Image-Guided Synergistic Cancer Therap, Analytical Chemistry, 2019, 通讯作者(10) Scaffolds biomimicking macrophages for a glioblastoma NIR-Ib imaging guided photothermal therapeutic strategy by crossing Blood-Brain Barrier, Biomaterials, 2019, 通讯作者(11) Rational Design of Perylenediimide-Substituted Triphenylethylene to Electron Transporting Aggregation-Induced Emission Luminogens (AIEgens) with High Mobility and Near-Infrared Emission, Advanced Functional Materials, 2018, 第 4 作者(12) Protein-modified conjugated polymer nanoparticles with strong near-infrared absorption: a novel nanoplatform to design multifunctional nanoprobes for dual-modal photoacoustic and fluorescence imaging, Nanoscale, 2018, 第 1 作者(13) Red/NIR‐Emissive Benzo[d]imidazole‐Cored AIEgens: Facile Molecular Design for Wavelength Extending and In Vivo Tumor Metabolic Imaging, Advanced Materials, 2018, 第 1 作者(14) Recombina nt-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging, Chemical Communications, 2018, 通讯作者(15) Ultrabright red AIEgens for two-photon vascular imaging with high resolution and deep penetration, Chemical Science, 2018, 第 1 作者(16) Polyyne bridged AIE luminogens with red emission: design, synthesis, properties and applications, Journal of Materials Chemistry B, 2017, 第 3 作者(17) Aptamer-Decorated Self-Assembled Aggregation-Induced Emission Organic Dots for Cancer Cell Targeting and Imaging, Analytical Chemistry, 2017, 第 1 作者(18) Ionization and Anion−π+ Interaction: A New Strategy for Structural Design of Aggregation-Induced Emission Luminogens, Journal of the American Chemical Society, 2017, 第 3 作者(19) Observation of Metal Nanoparticles for Acoustic Manipulation, Advanced Science, 2017, 第 7 作者(20) The synthesis of novel AIE emitters with the triphenylethene-carbazole skeleton and para-/meta-substituted arylboron groups and their application in efficient non-doped OLEDs, Journal of Materials Chemistry C, 2016, 第 4 作者(21) Iron oxide nanoparticles protected by NIR-active multidentate-polymers as multifunctional nanoprobes for NIRF/PA/MR trimodal imaging, Nanoscale, 2016, 通讯作者(22) Long-decay near-infrared-emitting doped quantum dots for lifetime-based in vivo pH imaging, Chemical Communications, 2015, 第 1 作者(23) Compact chelator-free Ni-integrated CuS nanoparticles with tunable near-infrared absorption and enhanced relaxivity for in vivo dual-modal photoacoustic/MR imaging, Nanoscale, 2015, 第 1 作者(24) Robust ICG Theranostic Nanoparticles for Folate Targeted Cancer Imaging and Highly Effective Photothermal Therapy, ACS Applied Materials & Interfaces, 2014, 第 6 作者(25) Aptamer-mediated indirect quantum dot labeling and fluorescent imaging of target proteins in living cells, Nanotechnology, 2014, 第 1 作者(26) Near-Infrared-Emitting Two-Dimensional Codes Based on Lattice-Strained Core/(Doped) Shell Quantum Dots with Long Fluorescence Lifetime, Advanced Materials, 2014, 第 1 作者(27) Smart Human Serum Albumin-Indocyanine Green Nanoparticles Generated by Programmed Assembly for Dual-Modal Imaging-Guided Cancer Synergistic Phototherapy, ACS NANO, 2014, 第 9 作者(28) Noninvasive Visualization of Respiratory Viral Infection Using Bioorthogonal Conjugated Near-Infrared-Emitting Quantum Dots, ACS NANO, 2014, 第 1 作者(29) Highly Bright and Compact Alloyed Quantum Rods with Near Infrared Emitting: a Potential Multifunctional Nanoplatform for Multimodal Imaging In Vivo, Advanced Functional Materials, 2014, 第 1 作者(30) Folate Receptor-Targeting Gold Nanoclusters as Fluorescence Enzyme Mimetic Nanoprobes for Tumor Molecular Colocalization Diagnosis, Theranostics, 2014, 第 6 作者(31) Near infrared fluorescence resonance energy transfer based aptamer biosensor for insulin detection in human plasma, Chemical Communications, 2014, 第 3 作者(32) Functionalized quantum dots induce proinflammatory responses in vitro: the role of terminal functional group-associated endocytic pathways, Nanoscale, 2013, 第 3 作者(33) Hybrid gold–gadolinium nanoclusters for tumor-targeted NIRF/CT/MRI triple-modal imaging in vivo, Nanoscale, 2013, 第 3 作者(34) One-step synthesis of peptide-programmed QDs as ready-to-use nanoprobes, Chemical Communications, 2013, 通讯作者(35) Single-Step Assembly of DOX/ICG Loaded Lipid–Polymer Nanoparticles for Highly Effective Chemo-photothermal Combination Therapy, ACS NANO, 2013, 第 8 作者(36) Protein-assisted fabrication of nano-reduced graphene oxide for combined in vivo photoacoustic imaging and photothermal therapy, Biomaterials, 2013, 第 9 作者(37) Polypeptide cationic micelles mediated co-delivery of docetaxel and siRNA for synergistic tumor therapy, Biomaterials, 2013, 第 6 作者(38) DNase-activatable fluorescence probes visualizing the degradation of exogenous DNA in living cells, Nanoscale, 2012, 第 3 作者(39) Click-Functionalized Compact Quantum Dots Protected by Multidentate-Imidazole Ligands: Conjugation-Ready Nanotags for Living-Virus Labeling and Imaging, Journal of the American Chemical Society, 2012, 第 1 作者(40) PEI protected aptamer molecular probes for contrast-enhanced in vivo cancer imaging, Biomaterials, 2012, 第 5 作者(41) Indocyanine green-loaded biodegradable tumor targeting nanoprobes for in vitro and in vivo imaging, Biomaterials, 2012, 第 5 作者(42) Cation exchange in aptamer-conjugated CdSe nanoclusters: a novel fluorescence signal amplification for cancer cell detection, Chemical Communications, 2012, 第 3 作者(43) A fast synthesis of near-infrared emitting CdTe/CdSe quantum dots with small hydrodynamic diameter for in vivo imaging probes, Nanoscale, 2011, 第 1 作者(44) Planar AIEgens with Enhanced Solid‐State Luminescence and ROS Generation for Multidrug‐Resistant Bacteria Treatment, Angewandte Chemie International Edition, 2002, 第 5 作者
科研活动
科研项目
( 1 ) 基于体内点击化学的光学纳米探针的构建及 其活体成像研究, 主持, 国家级, 2016-01--2018-12( 2 ) “点击化学”纳米探针用于病毒活体示踪研究, 主持, 省级, 2015-01--2016-12( 3 ) 基于点击化学的量子点原位生物标记新方法研究, 主持, 市地级, 2014-01--2015-12( 4 ) 王宽诚率先人才计划-卢嘉锡国际团队-纳米免疫与诊疗一体化国际团队, 参与, 部委级, 2019-01--2021-12( 5 ) 智能响应AIE-DNA 纳米火车载药系统用于精准纳米医学研究, 主持, 部委级, 2020-01--2021-12( 6 ) 仿生纳米/聚集态可视化诊疗一体化技术, 主持, 市地级, 2020-01--2021-12
参与会议
(1)AIE新材料在生物医疗技术方面的发展趋势 第十二届中国生物产业大会 2019-06-10(2)AIEgens-Based Photophysical Tools for Biomedical Research 第十六次中国暨国际生物物理大会 2018-08-24(3)Aptamer-AIE Dots: A Promising Tumor-Targeting Nanoprobe for Translational Medicine 2017-06-21
合作情况
中国香港-香港科技大学/香港大学/香港城市大学
中国澳门-澳门大学/澳门科技大学
澳大利亚-新南威尔士大学
意大利-米兰大学