(1)  Genetics and Breeding Studies of Mollusks: 
Development of microsatellites and mtDNA markers, Genetic polymorphism and population structure analysis; Monitoring and assessment of genetic changes over breeding practices, species identification; construction of linkage maps. Oysters breeding and strain development using strategy of family, mass selections, polyploid induction and hybridization; Breeding and genetics studies of giant clams etc., culture and resources restoration.
(2)  Gene and Genomics Studies of Mollusks: 
Studies of mollucan traits’ expression mechanisms using molecular biology and bioinformatic technologies, as well as transcriptome, DGE and proteomics approach; Research for the functions and regulations of trait-related genes employing cloning and expression analysis, providing useful gene, genomic information and molecular tools for trait resolving and strain development.
(3)  Mitochondrial Genome and Molecular Phylogenetics in Mollusks: 
Studies of the evolutionary patterns in mitochondrial gene content and genome structure by comparative mitogenomic analyses of mollusks under phylogenetic framework; inferring phylogenetic relationships for species at different levels using complete mitogenomic DNA sequences.

1979.09-83.06,  BSc,  Hunan Normal University, Major: Biology;
1983.09-86.06,  MSc, Shandong University, Major: Developmental Biology;
1994.09-97.06,  Ph.D, Ocean University of Qingdao, Major: Genetics in Fisheries.

1986.07-89.11: Teaching Assistant,  College of Fisheries, Ocean Univ. of Qingdao;
1989.12-94.11: Assistant Professor, College of Fisheries, Ocean Univ. of Qingdao;
1994.12-97.11: Associate Professor, College of Fisheries, Ocean Univ. of Qingdao;
1997.12-03.10: Professor, College of Fisheries, Ocean Univ. of Qingdao;
2005.1-Present: Professor,  Department of Marine Biology, South China Sea Institute of Oceanology, CAS.

1997.08-98.12: Postdoctoral Fellow, College of Marine Studies, University of Delaware, USA ;
2000.09-01.02: Visiting Scholar, Inst. Marine & Coastal Sciences, The State University of New Jersey, USA;
2001.06-04.12: Senior Research Associate, IMCS, The State University of New Jersey, USA. 

1986.07-89.11: Teaching Assistant,  College of Fisheries, Ocean Univ. of Qingdao;
1989.12-94.11: Assistant Professor, College of Fisheries, Ocean Univ. of Qingdao;
1994.12-97.11: Associate Professor, College of Fisheries, Ocean Univ. of Qingdao;
1997.12-03.10: Professor, College of Fisheries, Ocean Univ. of Qingdao;

*  Member of steering committee, World Oyster Society;

*  Associate editor of 《Aquatic Living Resources》;

*  Executive member of the council, Chinese Society of Malacology;
*  Director, Mariculture Experimental Station in Zhanjiang, CAS; 
*  Review panelist for International Science & Technology Cooperation Program of China, Ministry of Sciences and Technology of China;

*  Research Professor in Breeding Science, National Research & Development Center for Mollusk Fisheries Industrial Technology;

*  Member of National Shellfisheries Association, USA.

*  Editorial board member of 《Journal of Tropical Oceanology》, China  

1.         Mao F., K. Liu, Y. Lin, Z. He, J. Li, Z. Xiang, Y. Zhang* and Z. Yu*, 2020, Opsonic character of the plasma proteins in phagocytosis-dependent host response to bacterial infection in a marine invertebrate, Crassostrea gigas. Develop. Comp. Immunol. 106 :103596

2.         Zhou Z., J. Li, Y. Qin, Y. Zhou, Y. Zhang*, Z. Yu* etc., 2020, Artificial interspecific hybridization of two giant clams, Tridacna squamosa and Tridacna crocea, in the south China sea. Aquaculture, 515:734581.

3.         Liu, Y., Mao F., X. Zhang, Z. He, J. Li, Z. Xiang, Y. Zhang* and Z. Yu*, 2020, Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti-bacterial Defense of Crassostrea hongkongensis. Frontiers in Immunology. 11:416.

4.         Zhang, Y., H. Ma. J. Li, Z.. Zhou, Y. Qin, Z. Yu* etc., 2020, Analysis of inbreeding depression on performance traits of three giant clams (Tridacna derasa, T. squamosa, and T. crocea) in the South China Sea. Aquaculture, 521: 735023.

5.         Liu, Y., Mao F., X. Zhang, Z. He, J. Li, Z. Xiang, Y. Zhang* and Z. Yu*, 2020, TRAF6 suppresses the apoptosis of hemocytes by activating pellino in Crassostrea hongkongensis. Develop. Comp. Immunol.  103:103501.

6.         Qin, Y., Zhang, Y., H. Ma. J. Li, Z.. Zhou, Z. Yu* etc., 2020, Characterization and functional analysis of a caspase 3 gene: Evidence that ChCas 3 participates in the regulation of apoptosis in Crassostrea hongkongensis. Fish & Shellfish Immunology, 98:122-129.

7.         Zhang, Y., Y. Qin, J. Li, Z.. Zhou, S. Xiao, Z. Yu* etc., 2019, Gametogenesis From the Early History Life Stages of the Kumamoto Oyster Crassostrea sikamea and Their Breeding Potential Evaluation. Frontiers in Physiology, 5(10) :524.

8.         Ma, H., Y. Zhang, S. Xiao, Y. Zhang, Z. Xiang and Z. Yu* etc., 2019, The complete mitochondrial genome of giant clam, Hippopus hippopus (Cardiidae: Tridacninae). Conservation Genetics Resources. 11(3) : 263 -266.

9.         Wu, X., Zhang, Y., Y. Qin, S. Xiao, Z. Yu* etc., 2019, Comparative studies of the growth, survival, and reproduction of diploid and triploid Kumamoto oyster, Crassostrea sikamea.  J World Aquacult Soc. 1-12.

10.     Qin, Y., Y. Zhang, R. Mo, Y. Zhang*, Z. Yu* et al, 2019, Influence of ploidy and environment on grow-out traits of diploid and triploid Hong Kong oysters Crassostrea hongkongensis in southern China. Aquaculture, 507: 108-118.

11.     Mao F., Y. Lin, Z. He, J. Li, Z. Xiang, Y. Zhang* and Z. Yu*, 2018, Dual roles of cystatin A in the immune defense of the pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 75:190-197.

12.     Qin, Y., Zhang, Y., H. Ma. J. Li, S. Xiao, Z. Yu* etc., 2018, Comparison of the Biochemical Composition and Nutritional Quality nBetween Diploid and Triploid Hong Kong Oysters, Crassostrea hongkongensis. Frontiers in Physiology, 9 :1674.

13.     Ma, H., L. Lin, Y. Zhang, W. Shi and Z. Yu*, 2018, The complete mitochondrial genome sequence of the giant clam Tridacna derasa (Tridacnidae: Tridacna). Mitochondrial DNA Part B. https://doi.org/10.1080 /23802359.2018.

14.     Li, J., Zhang, Y., Zhang, Y., Mao F., S. Xiao, Z. Xiang, Z. Yu* et al, 2018, A Lysin motif (LysM)-containing protein from Hong Kong oyster, Crassostrea hongkongensis functions as a pattern recognition protein and an antibacterial agent. Gene, 674 :134–142.

15.    Li, J., Zhang, Y., Y. Qin, Mao F., Y. Lin, Y. Zhang, Z. Yu* et al, 2018, The first morphologic and functional characterization of hemocytes in Hong Kong oyster, Crassostrea hongkongensis. Fish & Shellfish Immunology, 81:423-429.

16.     Qin, Y., S. Xiao, H. Ma. J. Li, Y. Zhang*, Z. Yu* etc., 2018, Effects of salinity and temperature on the timing of germinal vesicle breakdown and polar body release in diploid and triploid Hong Kong oysters, Crassostrea hongkongensis, in relation to tetraploid induction. Aquaculture Research, DOI: 10.1111/are.13833.

17.     Zhang, Y., Li, J., Zhang, Y., Ma, H., Xiao, S., Xiang, X. ans Z. Yu*, (2017) Performance evaluation of reciprocal hybrids derived from the two brackish oysters, Crassostrea hongkongensis and Crassostrea sikamea in southern China. Aquaculture 473 310-316.

18.     Zhang, Y., Li, J., Qin, Y., Zhou, Y., Zhang, Y., Yu, Z*. 2017, A comparative study of the survival, growth and gonad development of the diploid and triploid Hong Kong oyster, Crassostrea hongkongensis (Lam & Morton 2003). Aquaculture Research, 48(5): 2453-2462.

19.     Zhang, Y., Zhang, Y., Li, J., Wang, Z., Yan, X., Yu, Z*.  2017, Incomplete sterility of hybrids produced by Crassostrea hongkongensis female× Crassostrea gigas male crosses. Aquaculture Research, 48(3): 1351-1358.

20.     Zhang, Y., Y. Zhang, J. Li, Z. Yu*, 2017, Morphological and molecular evidence of hybridization events between two congeneric oysters, Crassostrea hongkongensis and C. ariakensis , in southern China. J. Mollus. Stud. 83(1):123-128.

21.     Zhang, Y., Y. Zhang, J. Li, S. Xiao, Z. Xiang, Z. Wang*, X. Yan, Z. Yu*, 2016, Artificial interspecific backcrosses between the hybrid of female Crassostrea hongkongensis × male C. gigas and the two parental species. Aquaculture, 450:95-101.

22.     Zhang, Y., J. Su, J. Li, Y. Zhang, S. Xiao, Z. Yu*, 2016, Survival and growth of reciprocal crosses between two stocks of the Hong Kong oyster Crassostrea hongkongensis (Lam & Morton, 2003) in southern China. Aquaculture Research, 48:2344-2354.

23.     Zhang, Y., J. Li, Y. Qin, Y. Zhou, Y. Zhang, Z. Yu*, 2016, A comparative study of the survival, growth and gonad development of the diploid and triploid Hong Kong oyster, Crassostrea hongkongensis (Lam & Morton 2003). Aquaculture Research, 48:2353-2362.

24.     Li, J. , Y. Zhang, Y. Liu, Y. Zhang, S. Xiao, Z. Yu*, 2016, Co-expression of heat shock protein (HSP) 40 and HSP70 in Pinctada martensii response to thermal, low salinity and bacterial challenges. Fish Shellfish Immunol. 48: 239-243.

25.     Wang, F., S. Xiao, Zhang, Y., Y. Zhang, Y. Liiu, Y. Yan, Z. Xiang, Z. Yu*, 2015, ChAkt1 involvement in orchestrating the immune and heat shock responses in Crassostrea hongkongensis: Molecular cloning and functional characterization. Fish Shellfish Immunol. 4: 1015-1023.

26.     Tong, Y., Y. Zhang*, J. Huang, S. Xiao, Y. Zhang, Jun Li, J. Chen, Z. Yu*, 2015, Transcriptomics Analysis of Crassostrea hongkongensis for the Discovery of Reproduction-Related Gene. PLoS One, 10(8):e0134280.

27.     Xu, F., Y. Zhang*, J. Li, Y. Zhang, Z. Xiang, Z. Yu, 2015, Expression and Function analysis of two Naturally Truncated MyD88 variants in the Pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 45:510-516.

28.     Xu, F., J. Li, Y. Zhang, X. Li, Y. Zhang*, Z. Xiang, Z. Yu*, 2015, CgIκB3, the third novel inhibitor of NF-kappa B (IκB) protein, is involved in the immune defense of the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 46:648-655.

29.     Zhang, Y., Y. Zhang, J. Li,  Z. Wang, X. Yan, Z. Yu*, 2015, Incomplete sterility of hybrids produced by Crassostrea hongkongensis female x Crassostrea gigas male crosses. Aquaculture Res. DOI: 10.1111/ are.12941

30.     Qu, F., Z. Xiang, F. Wang, Y. Zhang, J. Li, Y. Zhang, S. Xiao, Z. Yu*, 2015, Identification and function of an evolutionarily conserved signaling intermediate in Toll pathways (ECSIT) from Crassostrea hongkongensis. Develop. Comp. Immunol.

31.     Zhang, Y., Y. Zhang,  Li J., Z. Wang*, X. Yan, Z. Yu*, 2015, Phenotypic trait of Crassostrea hongkongensis♀× C. angulata♂ hybrids in southern China. Aquaculture Research, DOI:10.1111/are.12787.

32.     Qu, , F., Z. Xiang, F. Wang, Y. Zhang, Y. Tong, J. Li, Y. Zhang, Z. Yu*, 2015, A novel molluscan Fos gene with immune defense function identified in the Hong Kong oyster, Crassostrea hongkongensis. Develop. Comp. Immunol. 51:194-201.

33.     Li, J. , Y. Zhang, Y. Zhang, Y. Liu, Z. Xiang, F. Qu, Z. Yu, 2015, Cloning and characterization of three suppressors of cytokine signaling (SOCS) genes from the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 44: 525–532.

34.     Qu, F., Xiang, Z., F. Wang, L. Qi, F. Xu, S. Xiao and Z. Yu*, 2015, Prostaglandin E receptor 4 (PTGER4) involved in host protection against immune challenge in oyster, Crassostrea hongkongensis. Fish Shellfish Immunol. 42: 316–324.

35.     Xiang, Z., F. Qu, F. Wang, Y. Tong, S. Xiao, J. Li, Y. Zhang and Z. Yu*, 2015, ChBax/Bak as key regulators of the mitochondrial apoptotic pathway: Cloned and characterized in Crassostrea hongkongensis. Fish Shellfish Immunol. 42:225-232.

36.     Zhang, Y., J. Sun , H. Mu , J. Li ,Y. Zhang , F. Xu , Z. Xiang, P Y. Qian , J. W. Qiu* and Z. Yu*, 2015, Proteomic basis of stress responses in the gills of the Pacific oyster Crassostrea gigas. J. Proteome Res. 14, 304−317.

37.     Zhang, Y., Y. Zhang, Z. Wang*, X. Yan and Z. Yu*, 2014, Phenotypic trait analysis of diploid and triploid hybrids from female Crassostrea hongkongensis × male C. gigas. Aquaculture 434：307-314.

38.     Qu, F., Xiang Z., Zhang Y, Li J., Zhang Y, Z. Yu*, 2014, The identification of the first molluscan Akirin2 with immune defense function in the Hong Kong oyster Crassostrea hongkongensis. Fish Shellfish Immunol. 41: 455-465.

39.     Xiang, Z., F. Qu, , J. Li, F. Wang, Y. Zhang and Z. Yu*, 2014, Characteristic and functional analysis of a ficolin-like protein from the oyster Crassostrea hongkongensis. Fish Shellfish Immunol. 40: 514-523.

40.     Li, J., Y. Zhang, Y. Zhang, Z. X.iang, Y. Tong, F. Qu and Z. Yu*, 2014, Genomic characterization and expression analysis of five novel IL-17 genes in the Pacific oyster, Crassostrea gigas. Fish Shellfish Immunol. 40: 455-465.

41.     Zhang, Y., F. Yu, J. Li, Y. Tong, Y. Zhang and Z. Yu*, 2014, The first invertebrate RIG-I-like receptor (RLR) homolog gene in the pacific oyster Crassostrea gigas. Fish Shellfish Immunol. 40: 466-471.

42.     Zhang, Y., J. Li, F. Yu, Y. Tong, Y. Zhang, X. Zhi and Z. Yu*, 2014, Identification and functional characterization of SIMPL in Crassostrea gigas reveals its ancient origin and involvement in the regulation of Rel/NF-κB transcription activity. Fish Shellfish Immunol. 40: 239-244.

43.     Xia, J. X. Wu, S. Xiao, Z. Yu*, 2014, Mitochondrial DNA and morphological identification of a new cupped oyster species Crassostrea dianbaiensis (Bivalvia: Ostreidae) in the South China Sea. Aquat. Living Resour. 27, 41-48.

44.     Qu, , F., Xiang, Z., Z. Yu*, 2014, The first molluscan acute phase serum amyloid A (A-SAA) identified from oyster Crassostrea hongkongensis: Molecular cloning and functional characterization. Fish Shellfish Immunol.  39 (2014) 145-151.

45.     Huang, J., Y. Zhang, J. Li, Z. Yu*, 2014, Development of SNP markers in Crassostrea hongkongensis based on the next-generation sequencing and high resolution melting analysis. Conservation Genet Resour. 6:559–562.

46.     Xiang, Z., F. Qu, L. Qi, Y. Tong, J. Li, S. Xiao, Z. Yu*, 2014, Cloning and characterization of an apoptosis-related DNA fragmentation factor (DFF) from oyster, Crassostrea hongkongensis. Fish Shellfish Immunol. 38: 119–126.

47.     Wu, X., S. Xiao, Z. Yu*, 2013, Mitochondrial DNA and morphological identification of Crassostrea zhanjiangensis sp. nov. (Bivalvia: Ostreidae): a new species in Zhanjiang, China. Aquat. Living Resour. 26(4): 273-280.  

 

Dr. Yang Zhang (2009)，Associate Res Professor；
Research interest: Molecular immunology and molecualr biology of Mollusks；

Dr. Shu Xiao (2010)，Associate Res Professor；
Research interest：Molluscan propagation and breeding science；

Dr. Zhiming Xiang (2010)，Associate Res Professor；
Research interest：Molecular biology of Mollusks；

Dr. Yuehuan Zhang (2012), Associate Res Professor；
Research interest：Molluscan genetics and breeding science；
 
Dr. Jun Li (2014)，Associatet Res Professor；
Research interest：Molecular biology of Mollusks；

Dr. Haitao MA (2012), Assistant Res Professor；
Research interest：Population genetics and Breeding Studies

Dr. Fan Mao (2018)，Assistant Res Professor；
Research interest：Molecular immunology and molecualr biology of Mollusks.

Dr. Yanping Qin (2019), Assistant Res Professor；

Research interest：Molluscan breeding science & Genetics.

Annual meeting of National Shellfisheries Association (NSA;USA);
http://shellfish.org/
International Conference of Plant and Animal Genomes (PAG);
http://www.intlpag.org/
International Symposium on Genetics in Aquaculture (ISGA); 
International Oyster Symposium (IOS) of World Oyster Society (WOS);
http://www.worldoyster.org/index_e.html
World Aquaculture Society (WAS) Conference;
https://www.was.org/Main/Default.asp
World Congress of Malacology (WCM).
http://www.unitasmalacologica.org/congress.html

Prof. Patrick M. Gaffney
Director, Marine BioSciences Program, College of Marine & Earth Studies
University of Delaware, USA 
http://www.ceoe.udel.edu/people/profile.aspx?pgaffney

Prof. Ximing Guo
Haskin Shellfish Research Lab, Institute of Marine and Coastal Sciences
Rutgers University (The State University of New Jersey), USA
http://hsrl.rutgers.edu/people/faculty/xguo.htm

Prof. Pierre Boudry
Responsable du Laboratoire Physiologie des Invertébrés, 
Physiologie et Ecophysiologie des Mollusques Marins
Ifremer - Technopole de Brest-Iroise, France
http://annuaire.ifremer.fr/cv/15809/

Drs. Christopher Brown, Gary Wikfirs and Judy Li
Milford Laboratory, National Marine Fisheries Service,
NOAA, USA
http://www.nefsc.noaa.gov/aed/biotech

Prof. V. Thiyagarajan (Rajan)
School of Biological Sciences, The University of Hong Kong,
Hong Kong 
http://www.biosch.hku.hk/staff/rajan/rajan.htm

Prof. Jianbo Yao
Division of Animal & Nutritional Sciences, 
Davis College of Agriculture, Natural Resources and Design
West Virginia University, USA
http://reprophys.wvu.edu/faculty/yao

Prof. Dean Jerry
School of Marine and Tropical Biology
James Cook University, Australia 
http://www.jcu.edu.au/mtb/research/projects/JCUDEV_014224.html

Student recruitments:
Marine Biology;
Molecular Biology & Biotechnology;
Aquaculture.

Previous Students:
Jinhui Chen, Postdoctoral fellow (2011);
Jianjun Xia,  Ph.D student,  Marine Biology (2008);
Shu Xiao,  Ph.D student, Marine Biology (2010);
Lu Li, Ph.D student, Marine Biology (2011); 
HaItao Ma, Ph.D student, Marine Biology (2012); 
Shiping Wang, Master student, Marine Biology (2007);
Rui Ren, Master student, Marine Biology (2009); 
Xiaodong Xu, Master student, Marine Biology (2010); 
Dingkun Fu, Master student, Marine Biology (2010); Now Ph.D student in Australia; 
Xiaocui He, Master student, Marine Biology (2011);  Now Ph.D student in Germany;
Jun Li, Master student, Marine Biology (2011);
Feng Yu, Master student, Marine Biology (2012). 
Xiaoling Li, Master student, Marine Biology (2013).
Qiang Wan, Master student, Marine Biology (2014); 
Jiaomei Huang, Master student, Marine Biology (2014). 
 
Current Students:
Fufa Qu,  Ph.D student, Marine Biology;
Fan Mao, Ph.D student, Marine Biology;
Fengjiao Xu, Master student, Marine Biology;
Yin Liu, Master student, Marine Biology.
Fuxuan Wang, Master student, Marine Biology.