General

Jianping Xie, Doctorial Tutor, Zhengzhou Tobacco Research Institute of CNTC
Email: xiejp@ztri.com.cn
Telephone:  
Mobile phone:  
Address:   No.2 Fengyang Street, High-Tech Zone, Zhengzhou, P. R. China
Postcode:   450001

Research Areas

1. Flavor Theory and Analysis

2. Separation and Analysis of Complex System

3. Toxicological Analysis and Risk Assessment

Education

1. 1982-02--1985-01, Master of Science in Engineering, Tobacco Industrial Scientific Research Institute of the Ministry of Light Industry.

2. 1978-03--1982-01, Bachelor of Science, Nanjing Normal of University.

Honors & Distinctions

(1)2020 CNTC Award for Outstanding Contribution to Science and Technology.

(2)Application of nano synergistic technology in top quality and high efficiency production of flue-cured tobacco, 2016 Henan Scientific and Technical Achievement Award, second class.

(3)Study on tobacco additive safety evaluation system, 2015 CNTC award for Innovation and Contribution in Standard, first class.

(4)Establishment and application of cigarette risk assessment and control system, 2010 China National Scientific and Technical Progress Award, second class.

(5)Study on cigarette risk index system, 2009 CNTC Scientific and Technical Process Award, first class.

(6)Rapid analysis of volatile acids and volatile alkaloids in tobacco complex on HS-LPME/Capillary GC-TOF-MS, 2008 Henan Scientific and Technical Achievement Award, first class.

(7)Studies on Technologies of Removal of Harmful Components in Cigarette Smoke, 2004 China National Scientific and Technical Progress Award, second class.

(8)Studies on Technology of Improving Burley Tobacco Quality and Usability, 2003 China National Scientific and Technical Progress Award, second class.


Publications

   
Papers

1 Autophagy induced by low concentrations of crotonaldehyde promotes apoptosis and inhibits necrosis in human bronchial epithelial cells, Ecotoxicology and Environmental Safety, 2019, 167, 169-177.
2
 Highly hydrophilic carbon nanoparticles: uptake mechanism by mammalian and plant cells, RSC Advances, 2018, 8, 35246-35256.
3
 Acute exposure to crotonaldehyde induces dysfunction of immune system in male Wistar rats, the Journal of Toxicological Sciences, 2018, 43, 33-44.
4
 Steam distillation/drop-by-drop extraction with gas chromatography-mass spectrometry for fast determination of volatile components in jujube (Ziziphus jujuba Mill.) extract, Chemistry Central Journal, 2017, 11:101.
5
 Crotonaldehyde induces autophagy-mediated cytotoxicity in human bronchial epithelial cells via PI3K, AMPK and MAPK pathways, Environmental Pollution, 2017, 228, 287-296.
6
 Simultaneous determination of rhamnose, xylitol, arabitol, fructose, glucose,inositol, sucrose, maltose in jujube (Zizyphus jujube Mill.) extract: comparison of HPLC–ELSD,LC–ESI–MS/MS and GC–MS, Chemistry Central Journal, 2016, 10:25.
7
 TG-FTIR, Py-two-dimensional GC-MS with heart-cutting and LC-MS/MS to reveal hydrocyanic acid formation mechanisms during glycine pyrolysis, Journal of Thermal Analysis and Calorimetry, 2014,115, 667-673.
8
 Fluorescence evaluation of scavenging efficiency of antioxidants against reactive oxygen species (ROS) in cigarette smoke, Analytical Letters, 2013, 46, 682-693.
9
 Crotonaldehyde induces apoptosis in alveolar macrophages through intracellular calcium, mitochondria and p53 signaling pathways, Journal of Toxicological Sciences, 2013, 38, 1-10.
10
 Crotonaldehyde induces apoptosis and immunosuppression in alveolar macrophages, Toxicology in Vitro, 2013, 27, 128-137.
11
 Correlation of hydrogen cyanide formation with 2,5-diketopiperazine and nitrogen heterocyclic compounds from co-pyrolysis of glycine and glucose/fructose, Energy & Fuels, 2013, 27, 4723-4728.
12
 Crotonaldehyde-exposed macrophages induce IL-8 release from airway epithelial cells through NF-κ B and AP-1 pathways, Toxicology Letters, 2013, 26-34.
13
 A Probabilistic Risk Assessment Approach
Used to Prioritize Chemical Constituents in Mainstream Smoke of Cigarettes Sold in China , Regulatory Toxicology and Pharmacology, 2012, 62, 355-362.

14 Crotonaldehyde induces oxidative stress and caspase-dependent apoptosis in human bronchial epithelial cells., Toxicol. Lett, 2010, 195, 90-98.
15
 Gene expression profile and cytotoxicity of human bronchial epithelial cells exposed to crotonaldehyde. , Toxicol. Lett, 2010, 197, 113-122.
16
 Separation and detection of polar cuticular components from Oriental tobacco leaf by integration of normal-phase liquid chromatography fractionation with reversed-phase liquid chromatography-mass spectrometry.,  J. Sep. Sci., 2010, 33, 3429-3436.
17
 Extraction and derivatization in single drop coupled to MALDI-FTICR-MS for selective determination of small molecule aldehydes in single puff smoke., Anal. Chim. Acta , 2009, 638, 198-201.
18
 Determination of volatile organic acids in Oriental tobacco by needle-based derivatization headspace LPME coupled to gas chromatography/ mass spectrometry. , J. Chromatogr. A, 2008, 1179, 89-95.
19 Determination of nicotine in mainstream smoke on the single puff level by liquid-phase microextraction coupled to matrix-assisted laser desorption/ionization Fourier transform mass spectrometry., Rapid Commun. Mass Spectrom, 2006, 20, 2573-2578.

Monograph

1China Tobacco Science and Technology, China Light Industry Press, 2020

(2)Chemical components of tobacco and smoke, Chemical Industry Press, 2011

(3)Toxicological Assessment of 1,3-Butadiene and Crotonaldehyde, LAMBERT Academic Publishing, 2010

(4)Theory and method on evaluation of cigarette risk, Chemical Industry Press, 2009

(5)Theory and application of tobacco flavor, Chemical Industry Press, 2008


Conferences

(1)Situation and Future: Prospects for the development of tobacco science and technology, National Tobacco Science and Technology Innovation Conference, 2016

(2)Scientific Basis of Tobacco Research, Advanced Professional and Technical Personnel Training Course in Tobacco Industry, 2016.

(3)Development of a novel hazard index of mainstream cigarette smoke and its application on risk evaluation of cigarette products. CORESTA Congress 2008.