070302-分析化学
071010-生物化学与分子生物学
083100-生物医学工程

单细胞质谱多组学和成像研究
肿瘤代谢
环境毒理

2009-09--2013-06   中科院生态环境研究中心   博士
2006-09--2009-06   大连海事大学   硕士
2002-09--2006-06   沈阳工业大学   学士

   

2019-09~现在, 中国科学院深圳先进技术研究院医工所, 副研究员
2014-12~2019-07,香港浸会大学环境与生物分析国家重点实验室, 博士后
2013-09~2014-11,中科院生态环境研究中心环境化学与生态毒理学国家重点实验室, 博士后

   

[1] JACS Au. 2024,   通讯作者  
[2] Analytical chemistry. 2023,   通讯作者  
[3] Star Protocols. 2023,   通讯作者  
[4] Reviews of Environmental Contamination and Toxicology. 2023, 第 1 作者
[5] iScience. 2022,   通讯作者  
[6] Current Opinion in Chemical Biology. 2022, 第 1 作者
[7] Guo, Lei, Hu, Zhenxing, Zhao, Chao, Xu, Xiangnan, Wang, Shujuan, Xu, Jingjing, Dong, Jiyang, Cai, Zongwei. Data Filtering and Its Prioritization in Pipelines for Spatial Segmentation of Mass Spectrometry Imaging. ANALYTICAL CHEMISTRY[J]. 2021, 第 3 作者  通讯作者  93(11): 4788-4793, 
[8] Zhao, Chao, Yong, Ting, Zhang, Yinbin, Xiao, Yu, Jin, Yaofeng, Zheng, Chang, Nirasawa, Takashi, Cai, Zongwei. Breast cancer proliferation and deterioration-associated metabolic heterogeneity changes induced by exposure of bisphenol S, a widespread replacement of bisphenol A. JOURNAL OF HAZARDOUS MATERIALS[J]. 2021, 第 1 作者414: 
[9] 赵超, 蔡宗苇. 基于质谱成像和组学分析的环境毒理研究. 化学进展[J]. 2021, 第 1 作者
[10] Zhao, Chao, Xie, Peisi, Yong, Ting, Huang, Wei, Liu, Jianjun, Wu, Desheng, Ji, Fenfen, Li, Min, Zhang, Doudou, Li, Ruijin, Dong, Chuan, Ma, Juan, Dong, Zheng, Liu, Sijin, Cai, Zongwei. Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy. SCIENCE BULLETIN[J]. 2021, 第 1 作者66(6): 578-591, 
[11] The Innovation. 2021, 第 1 作者
[12] Zhao, Chao, Cai, Zongwei. Three-dimensional quantitative mass spectrometry imaging in complex system: From subcellular to whole organism. MASS SPECTROMETRY REVIEWS[J]. 2020, 第 1 作者41(3): 469-487, 
[13] 蔡宗苇, 赵超. 孕鼠PM2.5暴露如何影响后代行为变化？. 科学通报[J]. 2020, 第 2 作者65(34): 3849-3850, 
[14] Zhao, Chao, Yong, Ting, Zhang, Yinbin, Jin, Yaofeng, Xiao, Yu, Wang, Hailin, Zhao, Bin, Cai, Zongwei. Evaluation of the splenic injury following exposure of mice to bisphenol S: A mass spectrometry-based lipidomics and imaging analysis. ENVIRONMENT INTERNATIONAL[J]. 2020, 第 1 作者135: 
[15] Xie, Peisi, Zhao, Chao, Liang, Xiaoping, Huang, Wei, Chen, Yanyan, Cai, Zongwei. Preparation of Frozen Sections of Multicellular Tumor Spheroids Coated with Ice for Mass Spectrometry Imaging. ANALYTICAL CHEMISTRY[J]. 2020, 第 2 作者92(11): 7413-7418, 
[16] Zhao, Chao, Tang, Zhi, Chung, Arthur Chi Kong, Wang, Hailin, Cai, Zongwei. Metabolic perturbation, proliferation and reactive oxygen species jointly contribute to cytotoxicity of human breast cancer cell induced by tetrabromo and tetrachloro bisphenol A. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY[J]. 2019, 第 1 作者170: 495-501, 
[17] Huang, Wei, Zhao, Chao, Zhong, Huan, Zhang, Shoudong, Xia, Yiji, Cai, Zongwei. Bisphenol S induced epigenetic and transcriptional changes in human breast cancer cell line MCF-7. ENVIRONMENTAL POLLUTION[J]. 2019, 第 2 作者246: 697-703, http://dx.doi.org/10.1016/j.envpol.2018.12.084.
[18] Zhao Chao, Tang Zhi, Xie, Peisi, Lin Kaili, Arthur Chi Kong Chung, Cai Zongwei. Immunotoxic Potentials of Bisphenol F Mediated through Lipid Signaling Pathways on Macrophages. Environmental Science & Technology[J]. 2019, 第 1 作者
[19] Zhao, Chao, Zhu, Lin, Li, Ruijin, Wang, Hailin, Cai, Zongwei. Omics approach reveals metabolic disorders associated with the cytotoxicity of airborne particulate matter in human lung carcinoma cells. ENVIRONMENTAL POLLUTION[J]. 2019, 第 1 作者246: 45-52, http://dx.doi.org/10.1016/j.envpol.2018.11.108.
[20] Zhao, Chao, Xie, Peisi, Yang, Ti, Wang, Hailin, Chung, Arthur Chi Kong, Cai, Zongwei. Identification of glycerophospholipid fatty acid remodeling by using mass spectrometry imaging in bisphenol S induced mouse liver. CHINESE CHEMICAL LETTERS[J]. 2018, 第 1 作者29(8): 1281-1283, http://lib.cqvip.com/Qikan/Article/Detail?id=676285936.
[21] Zhao, Chao, Xie, Peisi, Yong, Ting, Wang, Hailin, Chung, Arthur Chi Kong, Cai, Zongwei. MALDI-MS Imaging Reveals Asymmetric Spatial Distribution of Lipid Metabolites from Bisphenol S-Induced Nephrotoxicity. ANALYTICAL CHEMISTRY[J]. 2018, 第 1 作者90(5): 3196-3204, http://ir.rcees.ac.cn/handle/311016/40978.
[22] Zhao, Chao, Xie, Peisi, Wang, Hailin, Cai, Zongwei. Liquid chromatography-mass spectrometry-based metabolomics and lipidomics reveal toxicological mechanisms of bisphenol F in breast cancer xenografts. JOURNAL OF HAZARDOUS MATERIALS[J]. 2018, 第 1 作者358: 503-507, http://dx.doi.org/10.1016/j.jhazmat.2018.05.010.
[23] Zhao, Chao, Tang, Zhi, Yan, Jiacheng, Fang, Jing, Wang, Hailin, Cai, Zongwei. Bisphenol S exposure modulate macrophage phenotype as defined by cytokines profiling, global metabolomics and lipidomics analysis. SCIENCE OF THE TOTAL ENVIRONMENT[J]. 2017, 第 1 作者592: 357-365, http://dx.doi.org/10.1016/j.scitotenv.2017.03.035.
[24] Zhao, Chao, Wang, Hailin, Zhao, Bailin, Li, Cuiping, Yin, Ruichuan, Song, Maoyong, Liu, Baodong, Liu, Zhen, Jiang, Guibin. Boronic acid-mediated polymerase chain reaction for gene- and fragment-specific detection of 5-hydroxymethylcytosine. NUCLEIC ACIDS RESEARCH[J]. 2014, 第 1 作者42(9): http://www.irgrid.ac.cn/handle/1471x/936401.
[25] Zhao Chao. Capillary Monolithic Bioreactor of Immobilizing Snake Venom Phosphodiesterase for Mass Spectrometry Based Oligodeoxynucleotide Sequencing. Analytical Chemistry. 2012, 第 1 作者

（1） Air Pollution, Climate, and Health: An Integrated Perspective on Their Interactions, Chapter 9: Airborne particulate matter and its organic components: Complex triggers of human disease, Elsevier, 2021-05, 第 1 作者

西安交通大学第二附属医院

复旦大学肿瘤医院